Dr. Stein's Blog
for ME/CFS, FM, ES, Long COVID and Chronic Pain
In Part 1 of this series, I explained the concept of hormesis: how a small, intermittent, well-timed stressor can leave your cells stronger than before, and how fasting and phytochemical-rich foods pu...
We hear and read constantly that stress is an enemy, something that causes inflammation, heart disease, ulcers and cancer. We are told it is something to eliminate, calm or avoid entirely. I watched p...
Practical, Low-Cost Approaches Backed by Longevity Research
Understanding nutrient-sensing pathways is valuable, but knowledge alone doesn't improve health. What matters is putting that knowledge int...
Understanding Insulin, mTOR, AMPK, and Sirtuins: The Master Switches of Cellular Health
Your body is constantly monitoring its nutritional state. Every cell contains sophisticated sensors that detect...
What the Science of Longevity Reveals About Inflammation, Cellular Damage, and Your Health
Most people think of aging as a separate concern from chronic illness, something that happens later, after y...
In my last blog post, I talked about a really tough, but common, problem: the shame that often comes with chronic illness. Being sick, and sometimes living with a disability, is already incredibly cha...
Here are four ways shame quietly seeps into your thoughts:
Many people navigating life with a chronic illness carry a burden that’s rarely spoken of. It’s not the pain, the crushing fatigue, the gnaw...
Key Takeaways
If you are taking medications or supplements that don’t seem to be helping—or are causing side effects—you may be wondering how to stop medications safely or taper them without withdraw...
Key Takeaways
- This article provides an evidence-based review + clinical opinion of antidepressant effectiveness and tolerability, written by a psychiatrist with 35+ years of clinical experience tre ...
Key Takeaways
-  Urolithin A (UA) is a gut-derived metabolite produced from ellagitannin-rich foods (e.g., pomegranates, berries), but only ~30–40% of people produce sufficient amounts naturally.
- Â U...
Key Takeaways
What this article examines
This article reviews peer-reviewed research published in Communications Biology (Nature group) evaluating whether intensive mind-body practices can produce me...
Key Takeaways
When faced with conflicting information about medications, supplements, and other medical interventions, it can be hard to tell which options truly offer more benefit than harm. In this...